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Zakhar Kogan
Zakhar Kogan

69 Followers

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Oct 1

IIT, products and…

IIT is a…preudoscience? So the famed integrated information theory, which I’ve found in Life 3.0 (Max Tegmark) had been called a pseudoscience for one reason: it’s challenging and, perhaps, impossible, to even test it. In an open letter, it’s called ambitious but a steaming pile of bullshit: > IIT predicts that it is…

2 min read

2 min read


Sep 17

7 minutes of Mira Murati

A great, great introduction to LLMs and transformers — and a chance to ogle at OpenAI’s CTO! Covering attention, tokens, RLHF etc in 7 minutes enough for most. Persistent Python Nicholas Carlini’s great addition to Python DS stack — an environment state freezing machine! Briefly, it’s a ~100 line script that allows…

2 min read

2 min read


Sep 3

Graph news

Cold water for AI You know what happens in cold water? Everything shrinks. Bing’s market share hasn’t grown at all. Bing’s share of search It’s still stuck at a lousy 3%. So did traffic to ChatGPT and other LLMs. What could be the possible reasons? People realize it’s no magic bullet — rather prone…

4 min read

Graph news
Graph news

4 min read


Aug 17

Brexanolone for postpartum depression

Another take by Psychopharmacology Institute. Brexanolone is a synthetic form of allopregnagolone, a GABA modulating neurosteroid The study had 216 participants, all women 18–45 with de novo MDD in their third trimester or within the first 4 weeks following delivery The drug was administered via a 60-hour injection (despite a…

3 min read

Though(t)s [2023–08–14]
Though(t)s [2023–08–14]

3 min read


Aug 11

[2023–08–11] News and links

AI flies a big-ass military drone (I like big drones and I cannot lie) Nothing particular on the algo: Autonomous Air Combat Operations team created algorithms for the flight that took millions of hours to mature in simulations Deployed a semi-autonomous traffic control system in late June (Capt. Terrence McKenna!) Combining MAOIs with… A not-so-brand-spanking-new prescriber’s guide. MAOIs remain…

2 min read

[2023–08–11] News and links
[2023–08–11] News and links

2 min read


Jul 31

Oncogenes

An oncogene infographics piece. Credits to CancerQuest, an AWESOME database of illustrated + comprehensive overviews on different cancer mechanics, e.g. immune system. Shorties on genes p53 factor The major player, mutated in about 50% of human cancers. ANKRD11 is a coactivator of P53. HER-2/neu HER-2/neu encodes for a cell surface receptor that can stimulate cell division…

2 min read

Mama, I just wrote a post…
Mama, I just wrote a post…

2 min read


Jul 11

Models for the mental & captagon & PLG

Mental models Paradox of unanimity

4 min read

Models for the mental & captagon & PLG
Models for the mental & captagon & PLG

4 min read


Jul 4

Mental models, 1/n

Okay, there are 40 of them, gotta start with something: Baader-Meinhof phenomenon, or Frequency Illusion Similar but contrary to inattentional blindness: you start seeing things you think of/search more often and think they’re more common. Hence motivated perception, the Secret, ‘Why is everyone speaking my language here arrghh’ etc etc. P.S. One of the links…

5 min read

Mental models, migraine etc etc.
Mental models, migraine etc etc.

5 min read


May 25

DMT, pharmacogenetics and cetera

*puffs* DMT MoA An awesome take by Andrew Gallimore on DMT’s MoA. I’d reckon it generalizes on a wider range of psychedelics, e.g. 5-MeO-DMT and psilocin/other tryptamines at least. Takeaways: Our brain is an error-reducing Bayesian predictive machine. Yeah. Brain connectivity Structural: actual physical wiring of the brain, the synaptic connections between neurons; Effective: the…

4 min read

DMT, pharmacogenetics and cetera
DMT, pharmacogenetics and cetera

4 min read


May 17

Attachment styles

Aand some interesting tips on therapy for each. Being attached to something someone is not anti-Buddhist and exclusive to BPD, it’s healthy and awesome if mutual — especially if you do it in style and in a healthy way 😌 As it turns out: Four attachment types have been identified…

6 min read

Attachment, hair and habits
Attachment, hair and habits

6 min read

Zakhar Kogan

Zakhar Kogan

69 Followers

Writing about oh so diverse things. You’re welcome @ https://t.me/ohmyboi, too!

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